Research summary:
We study epigenetic and transcription mechanisms of mammalian gene control during development and disease, with potential long-term applications in developing alternative, gene-based therapies. We facilitate the use of genome-wide data through the development of new computational methods and tools (theme 1) as well as perform integrative analysis of –omics data (theme 2). Alongside this, we collaborate with several experimental labs (theme 3). The three main themes of research along with a list of exemplar publications for each theme is below: