How well does the proprietary lipid force field of Schrödinger, Inc. actually work? Pretty well, if you don’t need divalent ions.
Phospholipids are quite a bit like hard-core headbangers: No matter what goes on below, the head whirls just the same.
Can you publish a meaningful MD simulation paper without running a single MD simulation? Absolutely!
Using open data to rapidly benchmark biomolecular simulations: Phospholipid conformational dynamics
H. S. Antila, T. M. Ferreira, O. H. S. Ollila, and M. S. Miettinen
Journal of Chemical Information and Modeling
61 938 (2021)